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These compounds may counteract the effects of excessive or insufficient dopaminergic transmission,   and are for that reason under interrogation for relevancy in neurological and psychiatric disorders characterized by altered dopaminergic transferring, such as Huntington's complaint HD. Pridopidine is in late-stage evolvement by Teva Pharmaceutical Industries who acquired the rights to the product from its creative developer NeuroSearch in The MermaiHD study examined the effects of pridopidine in patients with HD and the results showed after six months of treatment, pridopidine improved amount motor symptoms, although the primary endpoint of the study was not met.
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